Uterine / Endometrial Cancer

What it is

Uterine cancer refers to cancer that begins in the uterus, the organ where a baby grows during pregnancy. The most common type is endometrial cancer, which starts in the lining of the uterus (the endometrium). Most cases are diagnosed early, when treatment is most effective.
How it’s diagnosed
Diagnosis typically begins with a pelvic exam, followed by imaging (such as ultrasound) and a biopsy of the endometrium. If cancer is found, additional scans may be ordered to determine how far it has spread and to guide treatment.
Common symptoms

Some people experience symptoms, while others may not notice anything unusual. The most common signs include:

If you have one of these symptoms, that doesn’t necessarily mean you have cancer. However, even if symptoms feel vague, it’s worth having them evaluated—especially if they’re new or persistent.

Dr. Kothari’s Approach

Dr. Kothari believes in clear, collaborative care—where you’re informed and supported at every step. When treating uterine or endometrial cancer, she considers your overall health, family planning goals, and personal values before recommending a treatment plan.

Whenever possible, she uses minimally invasive surgery to remove the cancer while reducing recovery time. From initial diagnosis to long-term surveillance, she’s focused not just on the outcome — but on how you feel throughout the process.

Frequently Asked Questions

Is uterine cancer the same as endometrial cancer?

Endometrial cancer is the most common type of uterine cancer—it begins in the lining of the uterus (the endometrium). Other types, like uterine sarcomas, begin in the muscle or connective tissue of the uterus. The treatment and outlook can vary depending on the type.

Will I need radiation or chemotherapy?

This depends on the stage and type of your cancer. In most cases, surgery is the first step. After surgery, your care team will review the findings and determine if additional treatment—like radiation or chemotherapy—is needed. In some situations, these treatments are recommended before surgery.

Can I still get pregnant if I have uterine cancer?

In certain cases, it may be possible to preserve your uterus and your ability to carry a pregnancy. This is typically an option for select early-stage endometrial cancers and involves hormonal treatment followed by careful monitoring. Your treatment plan will depend on the type and stage of cancer and your reproductive goals.

Why didn’t my Pap smear detect uterine cancer?

Pap smears (and human papilloma virus or HPV testing) are designed to screen for cervical cancer, not uterine cancer. While uterine cancer is occasionally detected on a Pap test, it’s not a reliable screening tool for that purpose.

Will I go into menopause after surgery?
Can my ovaries be saved?

If your uterus is removed, you’ll no longer have menstrual periods—but you won’t be in menopause unless your ovaries are also removed. Whether your ovaries can be preserved depends on the type and stage of your cancer. In many early-stage cases, it’s possible to keep the ovaries and avoid early menopause.

Can uterine cancer run in families?

Yes. About 5–10% of uterine cancers are linked to inherited conditions. If you have a family history of uterine, ovarian, or colon cancer, you may be at higher risk. Genetic testing and counseling may be recommended as part of your care.